DecodeME collaboration 2025 'Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome'.

https://www.research.ed.ac.uk/en/publications/initial-findings-from-the-decodeme-genome-wide-association-study-

STUDY DESIGN AND SCOPE

The DecodeME study conducted the largest genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), comparing DNA from 15,579 UK patients with ME/CFS against 259,909 healthy controls. All participants were of European ancestry, and ME/CFS cases were strictly defined using Canadian Consensus and/or Institute of Medicine criteria requiring post-exertional malaise and professional diagnosis.